李菁
个人经历:
- 2016-1至今, 中国科学院西双版纳热带植物园, 生物信息组, 助理研究员
- 2013-7至2015-11 清华大学，博士后
- 2009-9至2011-9 中国科学院计算技术研究所，生物信息组，客座学者
- 2003-9至2009-7 清华大学， 生物学，博士
- 2000-9至2003-7 中国医学科学院北京协和医科大学，生物化学和分子生物学，硕士
- 1996-9至2000-7 武汉大学，生物学，学士
研究方向:
发表文章:
- Zhang X＃, Li J, Pan BZ, Chen W, Chen M, Tang M, Xu ZF＊, Liu C＊. Extended mining of the oil biosynthesis pathway in biofuel plant Jatropha curcas by combined analysis of transcriptome and gene interactome data.BMC Bioinformatics. 2021 Aug 18;22(Suppl 6):409.
- Li J＃, Zhang X＃, Liu C＊. The computational approaches of lncRNA identification based on coding potential: Status quo and challenges.Comput Struct Biotechnol J. 2020 Nov 19;18:3666-3677.
- Li J＃, Liu C＊.Coding or Noncoding, the Converging Concepts of RNAs.Front Genet. 2019 May 22;10:496.
- Wang J＃, Zhang X＃, Chen W＃, Hu X, Li J＊, Liu C＊.Regulatory roles of long noncoding RNAs implicated in cancer hallmarks.Int J Cancer. 2020 Feb 15;146(4):906-916.
- Chen W＃, Zhang G＃, Li J＃, Zhang X, Huang S, Xiang S, Hu X＊, Liu C＊. CRISPRlnc: a manually curated database of validated sgRNAs for lncRNAs.Nucleic Acids Res. 2019 Jan 8;47(D1):D63-D68.
- Li J＃, Xuan Z, Liu C＊.Long non-coding RNAs and complex human diseases.Int J Mol Sci. 2013 Sep 12;14(9):18790-808.
- Zhang X＃, Pan BZ＃, Chen M, Chen W, Li J, Xu ZF, Liu C＊. JCDB: a comprehensive knowledge base for Jatropha curcas, an emerging model for woody energy plants.BMC Genomics. 2019 Dec 24;20(Suppl 9):958.
- Zhang X＃, Wang J＃, Li J, Chen W, Liu C＊. CRlncRC: a machine learning-based method for cancer-related long noncoding RNA identification using integrated features.BMC Med Genomics. 2018 Dec 31;11(Suppl 6):120.
- Wang J＃, Zhang X＃, Chen W＃, Li J＊, Liu C＊. CRlncRNA: a manually curated database of cancer-related long non-coding RNAs with experimental proof of functions on clinicopathological and molecular features.BMC Med Genomics. 2018 Dec 31;11(Suppl 6):114.
- Wang P＃, Li J, Gao X, Zhang D, Li A, Liu C＊.Genome-Wide Screening and Characterization of the Dof Gene Family in Physic Nut (Jatropha curcas L.).Int J Mol Sci. 2018 May 29;19(6):1598.
- Zhang X＃, Li T, Wang J, Li J, Chen L, Liu C＊.Identification of Cancer-Related Long Non-Coding RNAs Using XGBoost With High Accuracy.Front Genet. 2019 Aug 9;10:735.
- Hu X＃, Chen W＃, Li J＃, Huang S, Xu X, Zhang X, Xiang S, Liu C＊.ZFLNC: a comprehensive and well-annotated database for zebrafish lncRNA.Database (Oxford). 2018 Jan 1;2018:bay114.
- Chen W＃, Zhang X＃, Li J＃, Huang S, Xiang S, Hu X＊, Liu C＊. Comprehensive analysis of coding-lncRNA gene co-expression network uncovers conserved functional lncRNAs in zebrafish.BMC Genomics. 2018 May 9;19(Suppl 2):112.
- Zhao G, Bu D, Liu C, Li J, Yang J, Liu Z, Zhao Y, Chen R＊.CloudLCA: finding the lowest common ancestor in metagenome analysis using cloud computing.Protein Cell. 2012 Feb;3(2):148-52.
- Liu C＃, Li J＃, Zhao Y＊.Exploring hierarchical and overlapping modular structure in the yeast protein interaction network.BMC Genomics. 2010 Dec 2;11 Suppl 4(Suppl 4):S17.
- Li J＃, Lu L, Wu F, Chen Xi, Niu B, Jiang Shi-bo＊, Chen YH＊. The interaction between the membrane-proximal external region and the N-trimer region of HIV-1 gp41: Involvement in viral fusion. Chinese Science Bulletin (现Science Bulletin). 2009, 54(10): 1707-12.
- Li J＃, Chen X, Huang J, Jiang S, Chen YH＊. Identification of critical antibody-binding sites in the HIV-1 gp41 six-helix bundle core as potential targets for HIV-1 fusion inhibitors.Immunobiology. 2009; 214(1):51-60.
- Li J＃, Chen X, Jiang S, Chen YH＊. Deletion of fusion peptide or destabilization of fusion core of HIV gp41 enhances antigenicity and immunogenicity of 4E10 epitope.Biochem Biophys Res Commun. 2008 Nov 7;376(1):60-4.
- Wu F, Yuan XY, Li J, Chen YH＊. The co-administration of CpG-ODN influenced protective activity of influenza M2e vaccine.Vaccine. 2009 Jul 9;27(32):4320-4.
- Huang JH, Yang HW, Liu S, Li J, Jiang S＊, Chen YH＊. The mechanism by which molecules containing the HIV gp41 core-binding motif HXXNPF inhibit HIV-1 envelope glycoprotein-mediated syncytium formation.Biochem J. 2007 May 1;403(3):565-71.
联系方式：