PI：刘长宁
个人经历:
- 2014至今，中国科学院西双版纳热带植物园，生物信息研究组，研究员
- 2011至2013，德克萨斯大学达拉斯分校，访问学者
- 2010至2014，中科院计算技术研究所，副研究员
- 2007至2010，中科院计算技术研究所，助理研究员
- 2006至2007，哈佛大学Dana Farber癌症研究所，访问学生
- 2002至2007，中科院计算技术研究所 生物信息学 博士（导师 李国杰院士、陈润生院士）
- 1996至2000，武汉大学 国家生物学基地班,学士（导师 黄诗笺教授）
研究方向:
主要从事生物信息学相关研究工作，特别是与非编码基因以及生物复杂网络相关的研究工作。围绕云南省丰富的药用植物和经济植物资源展开，基于高通量测序数据分析结合分子生物学实验的非模式植物功能基因组研究。
发表文章:
- X. Zhang, ... , C. Liu*. Extended mining of the oil biosynthesis pathway in biofuel plant Jatropha curcas by combined analysis of transcriptome and gene interactome data. BMC Bioinformatics (2021).
- X. Gao, ... , C. Liu*. Transcriptome analysis of Paris polyphylla var. yunnanensis illuminates the biosynthesis and accumulation of steroidal saponins in rhizomes and leaves. Phytochemistry (2020).
- J. Li, ... , C. Liu*. The computational approaches of lncRNA identification based on coding potential: status quo and challenges. Computational and Structural Biotechnology Journal (2020).
- J. Wang, ... , C. Liu*. Regulatory roles of long non-coding RNAs implicated in cancer hallmarks. International Journal of Cancer (2020).
- J. Li, …, C. Liu*. Dynamic Expansion and Functional Evolutionary Profiles of Plant Conservative Gene Family SBP-Box in Twenty Two Flowering Plants and the Origin of miR156. Biomolecules (2020).
- W. Chen, …, C. Liu*. CRISPRlnc: a manually curated database of validated sgRNAs for lncRNAs. Nucleic Acids Research (2019).
- X. Zhang, …, C. Liu*. JCDB: a comprehensive knowledge base for Jatropha curcas, an emerging model for woody energy plants. BMC Genomics (2019).
- J. Li, C. Liu*. Coding or noncoding, the converging concepts of RNAs. Frontiers in Genetics (2019).
- X. Zhang, …, C. Liu*. Identification of cancer-related long non-coding RNAs using XGBoost with high accuracy. Frontiers in Genetics (2019).
- J. Li, …, C Liu*. Genome-wide identification, phylogeny, and expression analysis of the SBP-box gene family in Euphorbiaceae. BMC Genomics (2019)
- P. Wang, ..., C. Liu*. Genome-Wide Screening and Characterization of the Dof Gene Family in Physic Nut (Jatropha curcas L.). International Journal of Molecular Sciences (2018).
- W. Chen, ..., C. Liu*. Comprehensive analysis of coding-lncRNA gene co-expression network uncovers conserved functional lncRNAs in zebrafish. BMC Genomics (2018).
- Y. Li, ..., C. Liu*. Genome-wide Identification, Characterization and Expression Profiling of the Legume BZR Transcription Factor Gene Family. Frontiers in Plant Science (2018).
- X. Gao, ..., C. Liu*. Comparative chloroplast genomes of Paris Sect. Marmorata: insights into repeat regions and evolution implications. BMC Genomics (2018).
- J. Wang, ..., C. Liu*. CRlncRNA: a manually curated database of cancer-related long non-coding RNAs with experimental proof of functions on clinicopathological and molecular features. BMC Medical Genomics (2018).
- X. Zhang, ..., C. Liu*. CRlncRC: a novel machine learning method for cancer-related long noncoding RNA identification based on integrated features. BMC Medical Genomics (2018).
- X. Hu, …, C. Liu*. ZFLNC: a comprehensive and well-annotated database for zebrafish lncRNA. Database (2018).
- J. Li, …, C. Liu*. Long Non-Coding Rnas and Complex Human Diseases. International Journal of Molecular Sciences (2013).
- Q. Liao#, C. Liu#, et al. Large-Scale Prediction of Long Non-Coding Rna Functions in a Coding-Non-Coding Gene Co-Expression Network. Nucleic Acids Research (2011).
- Q. Liao, ..., C. Liu* and Y. Zhao*. Ncfans: A Web Server for Functional Annotation of Long Non-Coding Rnas. Nucleic Acids Research (2011).
- C. Liu*, J. Li, et al. Exploring Hierarchical and Overlapping Modular Structure in the Yeast Protein Interaction Network. BMC Genomics (2010).
- X. Yuan#, C. Liu#, et al. Clustered Micrornas' Coordination in Regulating Protein-Protein Interaction Network. BMC Systems Biology (2009).
- S. He #, H. Su#, C. Liu#, et al. Microrna-Encoding Long Non-Coding Rnas. BMC Genomics (2008).
- S. He #, C. Liu#, et al. Noncode V2.0: Decoding the Non-Coding. Nucleic Acids Research (2008).
- Y. Zhao#, S. He#, C. Liu#, et al. Microrna Regulation of Messenger-Like Noncoding Rnas: A Network of Mutual Microrna Control. Trends in Genetics (2008).
- Z. Zhang#, C. Liu#, et al. Dynamic Changes in Subgraph Preference Profiles of Crucial Transcription Factors. PLoS Computational Biology (2006).
- C. Liu, et al. Noncode: An Integrated Knowledge Database of Non-Coding Rnas. Nucleic Acids Research (2005).
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